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m(6)A methylation reader IGF2BP2 activates endothelial cells to promote angiogenesis and metastasis of lung adenocarcinoma

BACKGROUND: Lung adenocarcinoma (LUAD) is a common type of lung cancer with a high risk of metastasis, but the exact molecular mechanisms of metastasis are not yet understood. METHODS: This study acquired single-cell transcriptomics profiling of 11 distal normal lung tissues, 11 primary LUAD tissues...

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Detalles Bibliográficos
Autores principales: Fang, Han, Sun, Qi, Zhou, Jin, Zhang, Huijuan, Song, Qiong, Zhang, Hua, Yu, Guohua, Guo, Ying, Huang, Chengyu, Mou, Yakui, Jia, Chuanliang, Song, Yingjian, Liu, Aina, Song, Kaiyu, Lu, Congxian, Tian, Ruxian, Wei, Shizhuang, Yang, Dengfeng, Chen, Yixuan, Li, Ting, Wang, Kejian, Yu, Yilan, Lv, Yufeng, Mo, Ke, Sun, Ping, Yu, Xiaofeng, Song, Xicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288689/
https://www.ncbi.nlm.nih.gov/pubmed/37353784
http://dx.doi.org/10.1186/s12943-023-01791-1