Lipocalin-2-mediated astrocyte pyroptosis promotes neuroinflammatory injury via NLRP3 inflammasome activation in cerebral ischemia/reperfusion injury

BACKGROUND: Neuroinflammation is a vital pathophysiological process during ischemic stroke. Activated astrocytes play a major role in inflammation. Lipocalin-2 (LCN2), secreted by activated astrocytes, promotes neuroinflammation. Pyroptosis is a pro-inflammatory form of programmed cell death that ha...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Juanji, Xu, Pengfei, Hong, Ye, Xie, Yi, Peng, Mengna, Sun, Rui, Guo, Hongquan, Zhang, Xiaohao, Zhu, Wusheng, Wang, Junjun, Liu, Xinfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288712/
https://www.ncbi.nlm.nih.gov/pubmed/37353794
http://dx.doi.org/10.1186/s12974-023-02819-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288712/
https://www.ncbi.nlm.nih.gov/pubmed/37353794
http://dx.doi.org/10.1186/s12974-023-02819-5

Ejemplares similares