Cargando…

Lipocalin-2-mediated astrocyte pyroptosis promotes neuroinflammatory injury via NLRP3 inflammasome activation in cerebral ischemia/reperfusion injury

BACKGROUND: Neuroinflammation is a vital pathophysiological process during ischemic stroke. Activated astrocytes play a major role in inflammation. Lipocalin-2 (LCN2), secreted by activated astrocytes, promotes neuroinflammation. Pyroptosis is a pro-inflammatory form of programmed cell death that ha...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Juanji, Xu, Pengfei, Hong, Ye, Xie, Yi, Peng, Mengna, Sun, Rui, Guo, Hongquan, Zhang, Xiaohao, Zhu, Wusheng, Wang, Junjun, Liu, Xinfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288712/ https://www.ncbi.nlm.nih.gov/pubmed/37353794 http://dx.doi.org/10.1186/s12974-023-02819-5

Ejemplares similares

Low-density lipoprotein receptor (LDLR) regulates NLRP3-mediated neuronal pyroptosis following cerebral ischemia/reperfusion injury
por: Sun, Rui, et al.
Publicado: (2020)

NLRP3 Inflammasome Activation-Mediated Pyroptosis Aggravates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats
por: Qiu, Zhen, et al.
Publicado: (2017)

Breast cancer susceptibility protein 1 (BRCA1) rescues neurons from cerebral ischemia/reperfusion injury through NRF2-mediated antioxidant pathway
por: Xu, Pengfei, et al.
Publicado: (2018)

Protective Effects of Remimazolam on Cerebral Ischemia/Reperfusion Injury in Rats by Inhibiting of NLRP3 Inflammasome-Dependent Pyroptosis
por: Shi, Min, et al.
Publicado: (2022)

Metformin protects against myocardial ischemia-reperfusion injury and cell pyroptosis via AMPK/NLRP3 inflammasome pathway
por: Zhang, Jing, et al.
Publicado: (2020)

Geniposide suppresses NLRP3 inflammasome-mediated pyroptosis via the AMPK signaling pathway to mitigate myocardial ischemia/reperfusion injury
por: Li, Haiyan, et al.
Publicado: (2022)

The Interplay between Autophagy and NLRP3 Inflammasome in Ischemia/Reperfusion Injury
por: Lv, Shuangyu, et al.
Publicado: (2021)

Corilagin alleviates intestinal ischemia/reperfusion-induced intestinal and lung injury in mice via inhibiting NLRP3 inflammasome activation and pyroptosis
por: Li, Wenlian, et al.
Publicado: (2022)

Microglial TREM-1 receptor mediates neuroinflammatory injury via interaction with SYK in experimental ischemic stroke
por: Xu, Pengfei, et al.
Publicado: (2019)

Inhibition of Dectin-1 Alleviates Neuroinflammatory Injury by Attenuating NLRP3 Inflammasome-Mediated Pyroptosis After Intracerebral Hemorrhage in Mice: Preliminary Study Results
por: Ding, Zhiquan, et al.
Publicado: (2022)

Role of NLRP3 Inflammasome in Myocardial Ischemia-Reperfusion Injury and Ventricular Remodeling
por: Shen, Shichun, et al.
Publicado: (2022)

Astragaloside IV Alleviates Cerebral Ischemia-Reperfusion Injury through NLRP3 Inflammasome-Mediated Pyroptosis Inhibition via Activating Nrf2
por: Xiao, Lan, et al.
Publicado: (2021)

Chlorogenic acid protects against myocardial ischemia–reperfusion injury in mice by inhibiting Lnc Neat1/NLRP3 inflammasome-mediated pyroptosis
por: Chai, Xin, et al.
Publicado: (2023)

Disruption of C/EBPβ-Clec7a axis exacerbates neuroinflammatory injury via NLRP3 inflammasome-mediated pyroptosis in experimental neuropathic pain
por: Wu, Dan, et al.
Publicado: (2022)

Inhibition of NLRP3 Inflammasome Ameliorates Cerebral Ischemia-Reperfusion Injury in Diabetic Mice
por: Hong, Pu, et al.
Publicado: (2018)

ADAM8 Activates NLRP3 Inflammasome to Promote Cerebral Ischemia-Reperfusion Injury
por: Lu, Hongwei, et al.
Publicado: (2021)

NLRP3 Inflammasome Activation: A Therapeutic Target for Cerebral Ischemia–Reperfusion Injury
por: Wang, Lixia, et al.
Publicado: (2022)

Lipocalin-2 may produce damaging effect after cerebral ischemia by inducing astrocytes classical activation
por: Zhao, Nan, et al.
Publicado: (2019)

The Role of Pyroptosis and Autophagy in Ischemia Reperfusion Injury
por: Zhao, Huijie, et al.
Publicado: (2022)

Paeonol regulates NLRP3 inflammasomes and pyroptosis to alleviate spinal cord injury of rat
por: Zhao, Houling, et al.
Publicado: (2022)

Puerarin ameliorates acute lung injury by modulating NLRP3 inflammasome-induced pyroptosis
por: Cai, Dasheng, et al.
Publicado: (2022)

Diabetes induces hepatocyte pyroptosis by promoting oxidative stress-mediated NLRP3 inflammasome activation during liver ischaemia and reperfusion injury
por: Shi, Chengyu, et al.
Publicado: (2020)

Mitochondrial dysfunction induces NLRP3 inflammasome activation during cerebral ischemia/reperfusion injury
por: Gong, Zhe, et al.
Publicado: (2018)

Dexmedetomidine attenuates myocardial ischemia-reperfusion injury in vitro by inhibiting NLRP3 Inflammasome activation
por: Huang, Yaru, et al.
Publicado: (2021)

The Role of NLRP3 Inflammasome Activation Pathway of Hepatic Macrophages in Liver Ischemia–Reperfusion Injury
por: Wu, Tong, et al.
Publicado: (2022)

Retracted: ADAM8 Activates NLRP3 Inflammasome to Promote Cerebral Ischemia-Reperfusion Injury
por: Healthcare Engineering, Journal of
Publicado: (2023)

TAK1 mediates neuronal pyroptosis in early brain injury after subarachnoid hemorrhage
por: Xu, Pengfei, et al.
Publicado: (2021)

Pyroptosis in NLRP3 inflammasome-related atherosclerosis
por: Zeng, Xiang, et al.
Publicado: (2022)

Astrocytic phagocytosis contributes to demyelination after focal cortical ischemia in mice
por: Wan, Ting, et al.
Publicado: (2022)

ROS-Mediated NLRP3 Inflammasome Activation in Brain, Heart, Kidney, and Testis Ischemia/Reperfusion Injury
por: Minutoli, Letteria, et al.
Publicado: (2016)

Hydroxychloroquine attenuates renal ischemia/reperfusion injury by inhibiting cathepsin mediated NLRP3 inflammasome activation
por: Tang, Tao-Tao, et al.
Publicado: (2018)

Hypoxic preconditioning reduces NLRP3 inflammasome expression and protects against cerebral ischemia/reperfusion injury
por: Pang, Yi-Qiang, et al.
Publicado: (2021)

Correction to: Dexmedetomidine attenuates myocardial ischemia-reperfusion injury in vitro by inhibiting NLRP3 Inflammasome activation
por: Huang, Yaru, et al.
Publicado: (2021)

TLR4 Enhances Cerebral Ischemia/Reperfusion Injury via Regulating NLRP3 Inflammasome and Autophagy
por: Mao, Li, et al.
Publicado: (2023)

NLRP3: Role in ischemia/reperfusion injuries
por: Ghafouri-Fard, Soudeh, et al.
Publicado: (2022)

A novel small molecular NLRP3 inflammasome inhibitor alleviates neuroinflammatory response following traumatic brain injury
por: Kuwar, Ram, et al.
Publicado: (2019)

Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway
por: Jia, Yifan, et al.
Publicado: (2020)

Sevoflurane Alleviates Myocardial Ischemia Reperfusion Injury by Inhibiting P2X7-NLRP3 Mediated Pyroptosis
por: Wu, Jiaxuan, et al.
Publicado: (2021)

Epimedium Aqueous Extract Ameliorates Cerebral Ischemia/Reperfusion Injury through Inhibiting ROS/NLRP3-Mediated Pyroptosis
por: Wu, Xiaoyu, et al.
Publicado: (2023)

Hydrogen Attenuates Myocardial Injury in Rats by Regulating Oxidative Stress and NLRP3 Inflammasome Mediated Pyroptosis
por: Yang, Hongxiao, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_c16pkfupvtpp80onfcemehsikv