NO-sensitive guanylyl cyclase discriminates pericyte-derived interstitial from intra-alveolar myofibroblasts in murine pulmonary fibrosis

BACKGROUND: The origin of αSMA-positive myofibroblasts, key players within organ fibrosis, is still not fully elucidated. Pericytes have been discussed as myofibroblast progenitors in several organs including the lung. METHODS: Using tamoxifen-inducible PDGFRβ-tdTomato mice (PDGFRβ-CreER(T2); R26tdT...

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Detalles Bibliográficos
Autores principales: Aue, Annemarie, Englert, Nils, Harrer, Leon, Schwiering, Fabian, Gaab, Annika, König, Peter, Adams, Ralf, Schmidtko, Achim, Friebe, Andreas, Groneberg, Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288756/
https://www.ncbi.nlm.nih.gov/pubmed/37349733
http://dx.doi.org/10.1186/s12931-023-02479-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288756/
https://www.ncbi.nlm.nih.gov/pubmed/37349733
http://dx.doi.org/10.1186/s12931-023-02479-2

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