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Ebola virus inclusion bodies are liquid organelles whose formation is facilitated by nucleoprotein oligomerization

Viral RNA synthesis of several non-segmented, negative-sense RNA viruses (NNSVs) takes place in inclusion bodies (IBs) that show properties of liquid organelles, which are formed by liquid–liquid phase separation of scaffold proteins. It is believed that this is driven by intrinsically disordered re...

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Detalles Bibliográficos
Autores principales: Bodmer, Bianca S., Vallbracht, Melina, Ushakov, Dmitry S., Wendt, Lisa, Chlanda, Petr, Hoenen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288931/
https://www.ncbi.nlm.nih.gov/pubmed/37306660
http://dx.doi.org/10.1080/22221751.2023.2223727