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Bayesian hierarchical model-based network meta-analysis to overcome survival extrapolation challenges caused by data immaturity

AIM: This research evaluated standard Weibull mixture cure (WMC) network meta-analysis (NMA) with Bayesian hierarchical (BH) WMC NMA to inform long-term survival of therapies. MATERIALS & METHODS: Four trials in previously treated metastatic non-small-cell lung cancer with PD-L1 >1% were used...

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Detalles Bibliográficos
Autores principales: Heeg, Bart, Verhoek, Andre, Tremblay, Gabriel, Harari, Ofir, Soltanifar, Mohsen, Chu, Haitao, Roychoudhury, Satrajit, Cappelleri, Joseph C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Becaris Publishing Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288968/
https://www.ncbi.nlm.nih.gov/pubmed/36651607
http://dx.doi.org/10.2217/cer-2022-0159