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Dystrophic cardiomyopathy: role of the cardiac myofilaments

Dystrophic cardiomyopathy arises from mutations in the dystrophin gene. Dystrophin forms part of the dystrophin glycoprotein complex and is postulated to act as a membrane stabilizer, protecting the sarcolemma from contraction-induced damage. Duchenne muscular dystrophy (DMD) is the most severe dyst...

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Detalles Bibliográficos
Autores principales: George, Thomas G., Hanft, Laurin M., Krenz, Maike, Domeier, Timothy L., McDonald, Kerry S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288979/
https://www.ncbi.nlm.nih.gov/pubmed/37362434
http://dx.doi.org/10.3389/fphys.2023.1207658