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Inflammatory mediators act at renal pericytes to elicit contraction of vasa recta and reduce pericyte density along the kidney medullary vascular network

Introduction: Regardless of initiating cause, renal injury promotes a potent pro-inflammatory environment in the outer medulla and a concomitant sustained decrease in medullary blood flow (MBF). This decline in MBF is believed to be one of the critical events in the pathogenesis of acute kidney inju...

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Detalles Bibliográficos
Autores principales: Lilley, Rebecca J., Taylor, Kirsti D., Wildman, Scott S. P., Peppiatt-Wildman, Claire M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288992/
https://www.ncbi.nlm.nih.gov/pubmed/37362447
http://dx.doi.org/10.3389/fphys.2023.1194803