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Inflammatory mediators act at renal pericytes to elicit contraction of vasa recta and reduce pericyte density along the kidney medullary vascular network
Introduction: Regardless of initiating cause, renal injury promotes a potent pro-inflammatory environment in the outer medulla and a concomitant sustained decrease in medullary blood flow (MBF). This decline in MBF is believed to be one of the critical events in the pathogenesis of acute kidney inju...
Autores principales: | Lilley, Rebecca J., Taylor, Kirsti D., Wildman, Scott S. P., Peppiatt-Wildman, Claire M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10288992/ https://www.ncbi.nlm.nih.gov/pubmed/37362447 http://dx.doi.org/10.3389/fphys.2023.1194803 |
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