Preclinical immunogenicity and protective efficacy of a SARS-CoV-2 RBD-based vaccine produced with the thermophilic filamentous fungal expression system Thermothelomyces heterothallica C1

INTRODUCTION: The emergency use of vaccines has been the most efficient way to control the coronavirus disease 19 (COVID-19) pandemic. However, the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern has reduced the efficacy of currently used vaccines. The r...

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Detalles Bibliográficos
Autores principales: Gonzalez-Hernandez, Mariana, Kaiser, Franziska Karola, Steffen, Imke, Ciurkiewicz, Malgorzata, van Amerongen, Geert, Tchelet, Ronen, Emalfarb, Mark, Saloheimo, Markku, Wiebe, Marilyn G., Vitikainen, Marika, Albulescu, Irina C., Bosch, Berend-Jan, Baumgärtner, Wolfgang, Haagmans, Bart L., Osterhaus, Albert D. M. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289020/
https://www.ncbi.nlm.nih.gov/pubmed/37359531
http://dx.doi.org/10.3389/fimmu.2023.1204834

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289020/
https://www.ncbi.nlm.nih.gov/pubmed/37359531
http://dx.doi.org/10.3389/fimmu.2023.1204834

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