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Immunization with a mucosal, post-fusion F/G protein-based polyanhydride nanovaccine protects neonatal calves against BRSV infection

Human respiratory syncytial virus (HRSV) is a leading cause of death in young children and there are no FDA approved vaccines. Bovine RSV (BRSV) is antigenically similar to HRSV, and the neonatal calf model is useful for evaluation of HRSV vaccines. Here, we determined the efficacy of a polyanhydrid...

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Detalles Bibliográficos
Autores principales: Maina, Teresia W., Grego, Elizabeth A., Broderick, Scott, Sacco, Randy E., Narasimhan, Balaji, McGill, Jodi L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289034/
https://www.ncbi.nlm.nih.gov/pubmed/37359514
http://dx.doi.org/10.3389/fimmu.2023.1186184