The cytotoxicity effect of 7-hydroxy-3,4-dihydrocadalene from Heterotheca inuloides and semisynthetic cadalenes derivates towards breast cancer cells: involvement of oxidative stress-mediated apoptosis

BACKGROUND: Heterotheca inuloides, traditionally employed in Mexico, has demonstrated anticancer activities. Although it has been proven that the cytotoxic effect is attributed to cadinane-type sesquiterpenes such as 7-hydroxy-3,4-dihydrocadalene, the mechanism of action by which these agents act in...

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Detalles Bibliográficos
Autores principales: Mendoza-Fuentes, Alan, González-Burgos, Elena, Aparicio Trejo, Omar Emiliano, Delgado-Lamas, Guillermo, Rodríguez-Chávez, José Luis, Pedraza-Chaverri, José, Gómez-Serranillos, M. Pilar, Araiza-Olivera, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289085/
https://www.ncbi.nlm.nih.gov/pubmed/37361049
http://dx.doi.org/10.7717/peerj.15586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289085/
https://www.ncbi.nlm.nih.gov/pubmed/37361049
http://dx.doi.org/10.7717/peerj.15586

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