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The cytotoxicity effect of 7-hydroxy-3,4-dihydrocadalene from Heterotheca inuloides and semisynthetic cadalenes derivates towards breast cancer cells: involvement of oxidative stress-mediated apoptosis
BACKGROUND: Heterotheca inuloides, traditionally employed in Mexico, has demonstrated anticancer activities. Although it has been proven that the cytotoxic effect is attributed to cadinane-type sesquiterpenes such as 7-hydroxy-3,4-dihydrocadalene, the mechanism of action by which these agents act in...
Autores principales: | Mendoza-Fuentes, Alan, González-Burgos, Elena, Aparicio Trejo, Omar Emiliano, Delgado-Lamas, Guillermo, Rodríguez-Chávez, José Luis, Pedraza-Chaverri, José, Gómez-Serranillos, M. Pilar, Araiza-Olivera, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289085/ https://www.ncbi.nlm.nih.gov/pubmed/37361049 http://dx.doi.org/10.7717/peerj.15586 |
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