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Protective effect of the novel calcineurin inhibitor voclosporin in experimental colitis

BACKGROUND AND AIMS: Acute severe steroid-refractory ulcerative colitis remains a medically challenging condition with frequent need of surgery. It can be treated with the calcineurin inhibitor cyclosporine A with the need for therapeutic drug monitoring and significant toxicity. Recently, a novel c...

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Detalles Bibliográficos
Autores principales: Lindemann, Aylin, Roth, Dominik, Koop, Kristina, Neufert, Clemens, Zundler, Sebastian, Atreya, Raja, Neurath, Markus F., Leppkes, Moritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289195/
https://www.ncbi.nlm.nih.gov/pubmed/37358998
http://dx.doi.org/10.3389/fmed.2023.1177450