Cargando…
Protective effect of the novel calcineurin inhibitor voclosporin in experimental colitis
BACKGROUND AND AIMS: Acute severe steroid-refractory ulcerative colitis remains a medically challenging condition with frequent need of surgery. It can be treated with the calcineurin inhibitor cyclosporine A with the need for therapeutic drug monitoring and significant toxicity. Recently, a novel c...
Autores principales: | Lindemann, Aylin, Roth, Dominik, Koop, Kristina, Neufert, Clemens, Zundler, Sebastian, Atreya, Raja, Neurath, Markus F., Leppkes, Moritz |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289195/ https://www.ncbi.nlm.nih.gov/pubmed/37358998 http://dx.doi.org/10.3389/fmed.2023.1177450 |
Ejemplares similares
-
Clinical Response to Vedolizumab in Ulcerative Colitis Patients Is Associated with Changes in Integrin Expression Profiles
por: Fuchs, Friederike, et al.
Publicado: (2017) -
Neutrophils prevent rectal bleeding in ulcerative colitis by peptidyl-arginine deiminase-4-dependent immunothrombosis
por: Leppkes, Moritz, et al.
Publicado: (2022) -
Oral voclosporin: novel calcineurin inhibitor for treatment of noninfectious uveitis
por: Roesel, Martin, et al.
Publicado: (2011) -
Interleukin 36 receptor-inducible matrix metalloproteinase 13 mediates intestinal fibrosis
por: Koop, Kristina, et al.
Publicado: (2023) -
Integrating Immunologic Signaling Networks: The JAK/STAT Pathway in Colitis and Colitis-Associated Cancer
por: Zundler, Sebastian, et al.
Publicado: (2016)