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Kaempferol inhibits SARS-CoV-2 invasion by impairing heptad repeats-mediated viral fusion

BACKGROUND: : The continuous evolution of SARS-CoV-2 has underscored the development of broad-spectrum prophylaxis. Antivirals targeting the membrane fusion process represent promising paradigms. Kaempferol (Kae), an ubiquitous plant flavonol, has been shown efficacy against various enveloped viruse...

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Detalles Bibliográficos
Autores principales: Gao, Junwei, Cao, Can, Shi, Mingfei, Hong, Shihao, Guo, Shijie, Li, Jing, Liang, Tengxiao, Song, Ping, Xu, Ruodan, Li, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier GmbH. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289257/
https://www.ncbi.nlm.nih.gov/pubmed/37421767
http://dx.doi.org/10.1016/j.phymed.2023.154942