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SARS-CoV-2 protein ORF8 limits expression levels of Spike antigen and facilitates immune evasion of infected host cells

Recovery from COVID-19 depends on the ability of the host to effectively neutralize virions and infected cells, a process largely driven by antibody-mediated immunity. However, with the newly emerging variants that evade Spike-targeting antibodies, re-infections and breakthrough infections are incre...

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Detalles Bibliográficos
Autores principales: Kim, Ik-Jung, Lee, Yong-ho, Khalid, Mir M., Chen, Irene P., Zhang, Yini, Ott, Melanie, Verdin, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289268/
https://www.ncbi.nlm.nih.gov/pubmed/37354973
http://dx.doi.org/10.1016/j.jbc.2023.104955