Cargando…
SARS-CoV-2 protein ORF8 limits expression levels of Spike antigen and facilitates immune evasion of infected host cells
Recovery from COVID-19 depends on the ability of the host to effectively neutralize virions and infected cells, a process largely driven by antibody-mediated immunity. However, with the newly emerging variants that evade Spike-targeting antibodies, re-infections and breakthrough infections are incre...
Autores principales: | Kim, Ik-Jung, Lee, Yong-ho, Khalid, Mir M., Chen, Irene P., Zhang, Yini, Ott, Melanie, Verdin, Eric |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289268/ https://www.ncbi.nlm.nih.gov/pubmed/37354973 http://dx.doi.org/10.1016/j.jbc.2023.104955 |
Ejemplares similares
-
Immune evasion via SARS-CoV-2 ORF8 protein?
por: Park, Matthew D.
Publicado: (2020) -
Structure of SARS-CoV-2 ORF8, a rapidly evolving immune evasion protein
por: Flower, Thomas G., et al.
Publicado: (2021) -
ORF9c and ORF10 as accessory proteins of SARS-CoV-2 in immune evasion
por: Zandi, Milad
Publicado: (2022) -
Structure of SARS-CoV-2 ORF8, a rapidly evolving coronavirus protein implicated in immune evasion
por: Flower, Thomas G., et al.
Publicado: (2020) -
The ORF8 protein of SARS-CoV-2 mediates immune evasion through down-regulating MHC-Ι
por: Zhang, Yiwen, et al.
Publicado: (2021)