High-Throughput Sequencing Data Reveal an Antiangiogenic Role of HNF4A-Mediated CACNA1A/VEGFA Axis in Proliferative Diabetic Retinopathy

PURPOSE: Proliferative diabetic retinopathy (PDR) is characterized by retinal new vessel formation, pointing to the importance of the antiangiogenic treatment in PDR. Hepatocyte nuclear factor 4A (HNF4A) has been highlighted to inhibit vascular endothelial growth factor (VEGF)-stimulated in vitro an...

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Detalles Bibliográficos
Autores principales: Yin, Yuan, Wu, Shuai, Niu, Lingzhi, Huang, Shiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Immunology and Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289276/
https://www.ncbi.nlm.nih.gov/pubmed/37342032
http://dx.doi.org/10.1167/iovs.64.7.32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289276/
https://www.ncbi.nlm.nih.gov/pubmed/37342032
http://dx.doi.org/10.1167/iovs.64.7.32

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