5hmC modification regulates R-loop accumulation in response to stress

R-loop, an RNA-DNA hybrid structure, arises as a transcriptional by-product and has been implicated in DNA damage and genomic instability when excessive R-loop is accumulated. Although previous study demonstrated that R-loop is associated with ten-eleven translocation (Tet) proteins, which oxidize 5...

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Detalles Bibliográficos
Autores principales: Xu, Xingyun, Wang, Junjie, Wang, Wenjuan, Zhang, Yutong, Wan, Bo, Miao, Zhigang, Xu, Xingshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289295/
https://www.ncbi.nlm.nih.gov/pubmed/37363169
http://dx.doi.org/10.3389/fpsyt.2023.1198502

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289295/
https://www.ncbi.nlm.nih.gov/pubmed/37363169
http://dx.doi.org/10.3389/fpsyt.2023.1198502

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