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Pathological BBB Crossing Melanin-Like Nanoparticles as Metal-Ion Chelators and Neuroinflammation Regulators against Alzheimer’s Disease

Inflammatory responses, manifested in excessive oxidative stress and microglia overactivation, together with metal ion-triggered amyloid-beta (Aβ) deposition, are critical hallmarks of Alzheimer’s disease (AD). The intricate pathogenesis causes severe impairment of neurons, which, in turn, exacerbat...

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Detalles Bibliográficos
Autores principales: Huang, Qianqian, Jiang, Chaoqing, Xia, Xue, Wang, Yufan, Yan, Chenxing, Wang, Xiaorong, Lei, Ting, Yang, Xiaotong, Yang, Wenqin, Cheng, Guo, Gao, Huile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAAS 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289297/
https://www.ncbi.nlm.nih.gov/pubmed/37363131
http://dx.doi.org/10.34133/research.0180