New structures of Class II Fructose-1,6-Bisphosphatase from Francisella tularensis provide a framework for a novel catalytic mechanism for the entire class

Class II Fructose-1,6-bisphosphatases (FBPaseII) (EC: 3.1.3.11) are highly conserved essential enzymes in the gluconeogenic pathway of microorganisms. Previous crystallographic studies of FBPasesII provided insights into various inactivated states of the enzyme in different species. Presented here i...

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Detalles Bibliográficos
Autores principales: Selezneva, Anna I., Harding, Luke N. M., Gutka, Hiten J., Movahedzadeh, Farahnaz, Abad-Zapatero, Celerino
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289334/
https://www.ncbi.nlm.nih.gov/pubmed/37352301
http://dx.doi.org/10.1371/journal.pone.0274723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289334/
https://www.ncbi.nlm.nih.gov/pubmed/37352301
http://dx.doi.org/10.1371/journal.pone.0274723

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