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The cytosolic N-terminal region of heterologously-expressed transmembrane channel-like protein 1 (TMC1) can be cleaved in HEK293 cells

Transmembrane channel-like protein 1 (TMC1) is a transmembrane protein forming mechano-electrical transduction (MET) channel, which transduces mechanical stimuli into electrical signals at the top of stereocilia of hair cells in the inner ear. As an unexpected phenomenon, we found that the cytosolic...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Soichiro, Kamino, Maho, Hamamura, Maho, Otsuguro, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289374/
https://www.ncbi.nlm.nih.gov/pubmed/37352201
http://dx.doi.org/10.1371/journal.pone.0287249