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The cytosolic N-terminal region of heterologously-expressed transmembrane channel-like protein 1 (TMC1) can be cleaved in HEK293 cells
Transmembrane channel-like protein 1 (TMC1) is a transmembrane protein forming mechano-electrical transduction (MET) channel, which transduces mechanical stimuli into electrical signals at the top of stereocilia of hair cells in the inner ear. As an unexpected phenomenon, we found that the cytosolic...
Autores principales: | Yamaguchi, Soichiro, Kamino, Maho, Hamamura, Maho, Otsuguro, Ken-ichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289374/ https://www.ncbi.nlm.nih.gov/pubmed/37352201 http://dx.doi.org/10.1371/journal.pone.0287249 |
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