Retrotransposon LINE-1 bodies in the cytoplasm of piRNA-deficient mouse spermatocytes: Ribonucleoproteins overcoming the integrated stress response

Transposable elements (TE) are mobile DNA sequences whose excessive proliferation endangers the host. Although animals have evolved robust TE-targeting defenses, including Piwi-interacting (pi)RNAs, retrotransposon LINE-1 (L1) still thrives in humans and mice. To gain insights into L1 endurance, we...

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Detalles Bibliográficos
Autores principales: De Luca, Chiara, Gupta, Anuj, Bortvin, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289378/
https://www.ncbi.nlm.nih.gov/pubmed/37307272
http://dx.doi.org/10.1371/journal.pgen.1010797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289378/
https://www.ncbi.nlm.nih.gov/pubmed/37307272
http://dx.doi.org/10.1371/journal.pgen.1010797

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