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Glucose-dependent effect of insulin receptor isoforms on tamoxifen antitumor activity in estrogen receptor-positive breast cancer cells

INTRODUCTION: Breast cancer is the most common malignancy in women, and it is linked to several risk factors including genetic alterations, obesity, estrogen signaling, insulin levels, and glucose metabolism deregulation. Insulin and Insulin-like growth factor signaling exert a mitogenic and pro-sur...

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Detalles Bibliográficos
Autores principales: Stella, Stefania, Massimino, Michele, Manzella, Livia, Parrinello, Nunziatina Laura, Vitale, Silvia Rita, Martorana, Federica, Vigneri, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289407/
https://www.ncbi.nlm.nih.gov/pubmed/37361518
http://dx.doi.org/10.3389/fendo.2023.1081831