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Glucose-dependent effect of insulin receptor isoforms on tamoxifen antitumor activity in estrogen receptor-positive breast cancer cells
INTRODUCTION: Breast cancer is the most common malignancy in women, and it is linked to several risk factors including genetic alterations, obesity, estrogen signaling, insulin levels, and glucose metabolism deregulation. Insulin and Insulin-like growth factor signaling exert a mitogenic and pro-sur...
Autores principales: | Stella, Stefania, Massimino, Michele, Manzella, Livia, Parrinello, Nunziatina Laura, Vitale, Silvia Rita, Martorana, Federica, Vigneri, Paolo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289407/ https://www.ncbi.nlm.nih.gov/pubmed/37361518 http://dx.doi.org/10.3389/fendo.2023.1081831 |
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