Cognitive effects of thalamostriatal degeneration are ameliorated by normalizing striatal cholinergic activity

The loss of neurons in parafascicular thalamus (Pf) and their inputs to dorsomedial striatum (DMS) in Lewy body disease (LBD) and Parkinson’s disease dementia (PDD) have been linked to the effects of neuroinflammation. We found that, in rats, these inputs were necessary for both the function of stri...

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Detalles Bibliográficos
Autores principales: Becchi, Serena, Chieng, Billy, Bradfield, Laura A., Capellán, Roberto, Leung, Beatrice K., Balleine, Bernard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289650/
https://www.ncbi.nlm.nih.gov/pubmed/37352346
http://dx.doi.org/10.1126/sciadv.ade8247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289650/
https://www.ncbi.nlm.nih.gov/pubmed/37352346
http://dx.doi.org/10.1126/sciadv.ade8247

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