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Cognitive effects of thalamostriatal degeneration are ameliorated by normalizing striatal cholinergic activity
The loss of neurons in parafascicular thalamus (Pf) and their inputs to dorsomedial striatum (DMS) in Lewy body disease (LBD) and Parkinson’s disease dementia (PDD) have been linked to the effects of neuroinflammation. We found that, in rats, these inputs were necessary for both the function of stri...
Autores principales: | Becchi, Serena, Chieng, Billy, Bradfield, Laura A., Capellán, Roberto, Leung, Beatrice K., Balleine, Bernard W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289650/ https://www.ncbi.nlm.nih.gov/pubmed/37352346 http://dx.doi.org/10.1126/sciadv.ade8247 |
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