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Drugging evolution of antibiotic resistance at a regulatory network hub
Evolution of antibiotic resistance is a world health crisis, fueled by new mutations. Drugs to slow mutagenesis could, as cotherapies, prolong the shelf-life of antibiotics, yet evolution-slowing drugs and drug targets have been underexplored and ineffective. Here, we used a network-based strategy t...
Autores principales: | Zhai, Yin, Pribis, John P., Dooling, Sean W., Garcia-Villada, Libertad, Minnick, P.J., Xia, Jun, Liu, Jingjing, Mei, Qian, Fitzgerald, Devon M., Herman, Christophe, Hastings, P.J., Costa-Mattioli, Mauro, Rosenberg, Susan M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289659/ https://www.ncbi.nlm.nih.gov/pubmed/37352342 http://dx.doi.org/10.1126/sciadv.adg0188 |
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