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Drugging evolution of antibiotic resistance at a regulatory network hub

Evolution of antibiotic resistance is a world health crisis, fueled by new mutations. Drugs to slow mutagenesis could, as cotherapies, prolong the shelf-life of antibiotics, yet evolution-slowing drugs and drug targets have been underexplored and ineffective. Here, we used a network-based strategy t...

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Detalles Bibliográficos
Autores principales: Zhai, Yin, Pribis, John P., Dooling, Sean W., Garcia-Villada, Libertad, Minnick, P.J., Xia, Jun, Liu, Jingjing, Mei, Qian, Fitzgerald, Devon M., Herman, Christophe, Hastings, P.J., Costa-Mattioli, Mauro, Rosenberg, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289659/
https://www.ncbi.nlm.nih.gov/pubmed/37352342
http://dx.doi.org/10.1126/sciadv.adg0188