Sequential apoptotic and multiplexed proteomic evaluation of single cancer cells

A potential cause of cancer relapse is pretreatment chemoresistant subpopulations. Identifying targetable features of subpopulations that are poorly primed for therapy-induced cell death may improve cancer therapy. Here, we develop and validate real-time BH3 profiling, a live and functional single-c...

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Detalles Bibliográficos
Autores principales: Lecky, Emmalyn, Mukherji, Atreyi, German, Rebecca, Antonellis, Gabriella, Lin, Jia-Ren, Yorsz, Michael, McQueeney, Kelley E., Ryan, Jeremy, Ng, Kimmie, Sicinska, Ewa, Sorger, Peter K., Letai, Anthony, Bhola, Patrick D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2023
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289660/
https://www.ncbi.nlm.nih.gov/pubmed/37352344
http://dx.doi.org/10.1126/sciadv.adg4128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289660/
https://www.ncbi.nlm.nih.gov/pubmed/37352344
http://dx.doi.org/10.1126/sciadv.adg4128

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