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Sequential apoptotic and multiplexed proteomic evaluation of single cancer cells
A potential cause of cancer relapse is pretreatment chemoresistant subpopulations. Identifying targetable features of subpopulations that are poorly primed for therapy-induced cell death may improve cancer therapy. Here, we develop and validate real-time BH3 profiling, a live and functional single-c...
Autores principales: | Lecky, Emmalyn, Mukherji, Atreyi, German, Rebecca, Antonellis, Gabriella, Lin, Jia-Ren, Yorsz, Michael, McQueeney, Kelley E., Ryan, Jeremy, Ng, Kimmie, Sicinska, Ewa, Sorger, Peter K., Letai, Anthony, Bhola, Patrick D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289660/ https://www.ncbi.nlm.nih.gov/pubmed/37352344 http://dx.doi.org/10.1126/sciadv.adg4128 |
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