Large Scale Screening and Quantitative Analysis of Site-Specific N-Glycopeptides from Human Serum in Early Alzheimer’s Disease Using LC-HCD-PRM-MS

Glycopeptide analysis by mass spectrometry may provide an important opportunity in discovery of biomarkers to aid in early detection of Alzheimer’s Disease (AD). In this work, we have used a NanoLC-Stepped-HCD-DDA-MS/MS platform and a NanoLC-Stepped-HCD-PRM-MS platform for large-scale screening and...

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Detalles Bibliográficos
Autores principales: Pan, Lingyun, Lin, Yu, Zhu, Jianhui, Zhang, Jie, Tan, Zhijing, Lubman, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289803/
https://www.ncbi.nlm.nih.gov/pubmed/37362028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289803/
https://www.ncbi.nlm.nih.gov/pubmed/37362028

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