Autophagosome membrane expansion is mediated by the N-terminus and cis-membrane association of human ATG8s

Autophagy is an essential catabolic pathway which sequesters and engulfs cytosolic substrates via autophagosomes, unique double-membraned structures. ATG8 proteins are ubiquitin-like proteins recruited to autophagosome membranes by lipidation at the C-terminus. ATG8s recruit substrates, such as p62,...

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Detalles Bibliográficos
Autores principales: Zhang, Wenxin, Nishimura, Taki, Gahlot, Deepanshi, Saito, Chieko, Davis, Colin, Jefferies, Harold BJ, Schreiber, Anne, Thukral, Lipi, Tooze, Sharon A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289813/
https://www.ncbi.nlm.nih.gov/pubmed/37288820
http://dx.doi.org/10.7554/eLife.89185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289813/
https://www.ncbi.nlm.nih.gov/pubmed/37288820
http://dx.doi.org/10.7554/eLife.89185

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