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Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicle Infusion for the Treatment of Respiratory Failure from COVID-19: A Randomized Placebo Controlled Dosing Clinical Trial

BACKGROUND: Bone marrow mesenchymal stem cell (BM-MSC)-derived extracellular vesicles (EVs), ExoFlo(TM), convey the immunomodulatory and regenerative properties of intact BM-MSC. This study aimed to determine the safety and efficacy of ExoFlo as treatment for moderate-to-severe Acute Respiratory Dis...

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Detalles Bibliográficos
Autores principales: Lightner, Amy L., Sengupta, Vikram, Qian, Sascha, Ransom, John T., Suzuki, Sam, Park, David J., Melson, Timothy I., Williams, Brian P., Walsh, James J., Awili, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier Inc under license from the American College of Chest Physicians. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289818/
https://www.ncbi.nlm.nih.gov/pubmed/37356708
http://dx.doi.org/10.1016/j.chest.2023.06.024