miR-33a Expression Attenuates ABCA1-Dependent Cholesterol Efflux and Promotes Macrophage-Like Cell Transdifferentiation in Cultured Vascular Smooth Muscle Cells

Recent evidence suggests that the majority of cholesterol-laden cells found in atherosclerotic lesions are vascular smooth muscle cells (VSMC) that have transdifferentiated into macrophage-like cells (MLC). Furthermore, cholesterol-laden MLC of VSMC origin have demonstrated impaired ABCA1-dependent...

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Detalles Bibliográficos
Autores principales: Esobi, Ikechukwu C., Oladosu, Olanrewaju, Echesabal-Chen, Jing, Powell, Rhonda R., Bruce, Terri, Stamatikos, Alexis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289877/
https://www.ncbi.nlm.nih.gov/pubmed/37359759
http://dx.doi.org/10.1155/2023/8241899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289877/
https://www.ncbi.nlm.nih.gov/pubmed/37359759
http://dx.doi.org/10.1155/2023/8241899

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