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miR-33a Expression Attenuates ABCA1-Dependent Cholesterol Efflux and Promotes Macrophage-Like Cell Transdifferentiation in Cultured Vascular Smooth Muscle Cells

Recent evidence suggests that the majority of cholesterol-laden cells found in atherosclerotic lesions are vascular smooth muscle cells (VSMC) that have transdifferentiated into macrophage-like cells (MLC). Furthermore, cholesterol-laden MLC of VSMC origin have demonstrated impaired ABCA1-dependent...

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Detalles Bibliográficos
Autores principales:	Esobi, Ikechukwu C., Oladosu, Olanrewaju, Echesabal-Chen, Jing, Powell, Rhonda R., Bruce, Terri, Stamatikos, Alexis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10289877/ https://www.ncbi.nlm.nih.gov/pubmed/37359759 http://dx.doi.org/10.1155/2023/8241899

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