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Adverse events with quetiapine and clarithromycin coprescription: A population‐based retrospective cohort study

BACKGROUND AND AIMS: Quetiapine is an atypical antipsychotic predominantly metabolized by the cytochrome P450 3A4 (CYP3A4) enzyme. We studied the risk of adverse events following coprescription of clarithromycin (a strong CYP3A4 inhibitor) versus azithromycin (not a CYP3A4 inhibitor) in quetiapine u...

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Detalles Bibliográficos
Autores principales: Yau, Kevin, McArthur, Eric, Jeyakumar, Nivethika, Tsobo Muanda, Flory, Kim, Richard B., Clemens, Kristin K., Wald, Ron, Garg, Amit X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290079/
https://www.ncbi.nlm.nih.gov/pubmed/37359413
http://dx.doi.org/10.1002/hsr2.1375