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Structure of human TRPV4 in complex with GTPase RhoA

Transient receptor potential (TRP) channel TRPV4 is a polymodal cellular sensor that responds to moderate heat, cell swelling, shear stress, and small-molecule ligands. It is involved in thermogenesis, regulation of vascular tone, bone homeostasis, renal and pulmonary functions. TRPV4 is implicated...

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Detalles Bibliográficos
Autores principales: Nadezhdin, Kirill D., Talyzina, Irina A., Parthasarathy, Aravind, Neuberger, Arthur, Zhang, David X., Sobolevsky, Alexander I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290124/
https://www.ncbi.nlm.nih.gov/pubmed/37353478
http://dx.doi.org/10.1038/s41467-023-39346-z