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Structure of human TRPV4 in complex with GTPase RhoA
Transient receptor potential (TRP) channel TRPV4 is a polymodal cellular sensor that responds to moderate heat, cell swelling, shear stress, and small-molecule ligands. It is involved in thermogenesis, regulation of vascular tone, bone homeostasis, renal and pulmonary functions. TRPV4 is implicated...
Autores principales: | Nadezhdin, Kirill D., Talyzina, Irina A., Parthasarathy, Aravind, Neuberger, Arthur, Zhang, David X., Sobolevsky, Alexander I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290124/ https://www.ncbi.nlm.nih.gov/pubmed/37353478 http://dx.doi.org/10.1038/s41467-023-39346-z |
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