Cellular senescence in white matter microglia is induced during ageing in mice and exacerbates the neuroinflammatory phenotype

Cellular senescence, a state of irreversible cell-cycle arrest caused by a variety of cellular stresses, is critically involved in age-related tissue dysfunction in various organs. However, the features of cells in the central nervous system that undergo senescence and their role in neural impairmen...

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Detalles Bibliográficos
Autores principales: Matsudaira, Tatsuyuki, Nakano, Sosuke, Konishi, Yusuke, Kawamoto, Shimpei, Uemura, Ken, Kondo, Tamae, Sakurai, Koki, Ozawa, Takaaki, Hikida, Takatoshi, Komine, Okiru, Yamanaka, Koji, Fujita, Yuki, Yamashita, Toshihide, Matsumoto, Tomonori, Hara, Eiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290132/
https://www.ncbi.nlm.nih.gov/pubmed/37353538
http://dx.doi.org/10.1038/s42003-023-05027-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290132/
https://www.ncbi.nlm.nih.gov/pubmed/37353538
http://dx.doi.org/10.1038/s42003-023-05027-2

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