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Treatment mechanism of immune triad from the repurposing drug against COVID-19

COVID-19 is an immune-mediated disease whose pathophysiology uses SAMHD1 tetramerization and cGAS–STING signaling, toll-like receptor 4 (TLR4) cascade, spike protein– inflammasome activation, and neuropilin 1 (NRP1) signaling. Variants of concern, such as SARS-CoV-2 Omicron Subvariants BQ.1, BQ.1.1,...

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Detalles Bibliográficos
Autor principal: Lee, Jong hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co. Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290163/
https://www.ncbi.nlm.nih.gov/pubmed/37388715
http://dx.doi.org/10.1016/j.tma.2023.06.005