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First‐in‐human clinical trial of allogeneic, platelet‐derived extracellular vesicles as a potential therapeutic for delayed wound healing

The release of growth factors, cytokines and extracellular matrix modifiers by activated platelets is an important step in the process of healthy wound healing. Extracellular vesicles (EVs) released by activated platelets carry this bioactive cargo in an enriched form, and may therefore represent a...

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Detalles Bibliográficos
Autores principales: Johnson, Jancy, Law, Sam Q. K., Shojaee, Mozhgan, Hall, Alex S., Bhuiyan, Sadman, Lim, Melissa B. L., Silva, Anabel, Kong, Karmen J. W., Schoppet, Melanie, Blyth, Chantelle, Ranasinghe, Hansi N., Sejic, Nenad, Chuei, Mun Joo, Tatford, Owen C., Cifuentes‐Rius, Anna, James, Patrick F., Tester, Angus, Dixon, Ian, Lichtfuss, Gregor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290200/
https://www.ncbi.nlm.nih.gov/pubmed/37353884
http://dx.doi.org/10.1002/jev2.12332