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Operationalising targeted next-generation sequencing for routine diagnosis of drug-resistant TB

BACKGROUND: Phenotypic drug susceptibility testing (pDST) for Mycobacterium tuberculosis can take up to 8 weeks, while conventional molecular tests identify a limited set of resistance mutations. Targeted next-generation sequencing (tNGS) offers rapid results for predicting comprehensive drug resist...

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Detalles Bibliográficos
Autores principales: Iyer, A., Ndlovu, Z., Sharma, J., Mansoor, H., Bharati, M., Kolan, S., Morales, M., Das, M., Issakidis, P., Ferlazzo, G., Hirani, N., Joshi, A., Tipre, P., Sutar, N., England, K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union Against Tuberculosis and Lung Disease 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290261/
https://www.ncbi.nlm.nih.gov/pubmed/37359066
http://dx.doi.org/10.5588/pha.22.0041