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Development of a method for isolating brain capillaries from a single neonatal mouse brain and comparison of proteomic profiles between neonatal and adult brain capillaries

BACKGROUND: The functions and protein expressions of the blood–brain barrier are changed throughout brain development following birth. This study aimed to develop a method to isolate brain capillaries from a single frozen neonatal mouse brain and elucidate the enrichment of brain capillaries by quan...

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Detalles Bibliográficos
Autores principales: Hamada, Yudai, Ogata, Seiryo, Masuda, Takeshi, Ito, Shingo, Ohtsuki, Sumio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290343/
https://www.ncbi.nlm.nih.gov/pubmed/37353852
http://dx.doi.org/10.1186/s12987-023-00449-w