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Homocysteine induces ferroptosis in endothelial cells through the systemXc(−)/GPX4 signaling pathway
OBJECTIVES: To investigate whether ferroptosis is involved in HCY-induced endothelial injury and the possible mechanism of HCY-induced ferroptosis. METHODS: EA. hy926 cells were cultured in vitro. Cells were intervened using HCY and Fer-1. The cells were divided into Control groups, HCY (4 mM), HCY...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290364/ https://www.ncbi.nlm.nih.gov/pubmed/37355559 http://dx.doi.org/10.1186/s12872-023-03342-4 |