Homocysteine induces ferroptosis in endothelial cells through the systemXc(−)/GPX4 signaling pathway

OBJECTIVES: To investigate whether ferroptosis is involved in HCY-induced endothelial injury and the possible mechanism of HCY-induced ferroptosis. METHODS: EA. hy926 cells were cultured in vitro. Cells were intervened using HCY and Fer-1. The cells were divided into Control groups, HCY (4 mM), HCY...

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Detalles Bibliográficos
Autores principales: Shi, Jiahao, Chen, Di, Wang, Zilin, Li, Shaolin, Zhang, Shuying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290364/
https://www.ncbi.nlm.nih.gov/pubmed/37355559
http://dx.doi.org/10.1186/s12872-023-03342-4

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