Fanca deficiency is associated with alterations in osteoclastogenesis that are rescued by TNFα

BACKGROUND: Hematopoietic stem cells (HSCs) reside in the bone marrow (BM) niche, which includes bone-forming and bone-resorbing cells, i.e., osteoblasts (OBs) and osteoclasts (OCs). OBs originate from mesenchymal progenitors, while OCs are derived from HSCs. Self-renewal, proliferation and differen...

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Detalles Bibliográficos
Autores principales: Oppezzo, Alessia, Monney, Lovely, Kilian, Henri, Slimani, Lofti, Maczkowiak-Chartois, Frédérique, Rosselli, Filippo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290407/
https://www.ncbi.nlm.nih.gov/pubmed/37355617
http://dx.doi.org/10.1186/s13578-023-01067-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290407/
https://www.ncbi.nlm.nih.gov/pubmed/37355617
http://dx.doi.org/10.1186/s13578-023-01067-7

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