Integrating Omics and CRISPR Technology for Identification and Verification of Genomic Safe Harbor Loci in the Chicken Genome

BACKGROUND: One of the most prominent questions in the field of transgenesis is ‘Where in the genome to integrate a transgene?’. Escape from epigenetic silencing and promoter shutdown of the transgene needs reliable genomic safe harbor (GSH) loci. Advances in genome engineering technologies combined...

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Detalles Bibliográficos
Autores principales: Dehdilani, Nima, Goshayeshi, Lena, Yousefi Taemeh, Sara, Bahrami, Ahmad Reza, Rival Gervier, Sylvie, Pain, Bertrand, Dehghani, Hesam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290409/
https://www.ncbi.nlm.nih.gov/pubmed/37355580
http://dx.doi.org/10.1186/s12575-023-00210-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10290409/
https://www.ncbi.nlm.nih.gov/pubmed/37355580
http://dx.doi.org/10.1186/s12575-023-00210-5

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